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Scientists have obtained their first three-dimensional look at a member of a large family of proteins that play a central role in the development of cystic fibrosis, can block the therapeutic effects of medications, and are also involved in a wide range of vital biological processes. The structure of this representative protein was solved by a team at the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California at Berkeley (UCB).

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Conditions and Diseases: Genetic Disorders: Cystic Fibrosis: CFTR and Genetic Mutations: Protein Structure of CFTR Unravelled  Previous
 

Protein Structure of CFTR Unravelled


Scientists have obtained their first three-dimensional look at a member of a large family of proteins that play a central role in the development of cystic fibrosis, can block the therapeutic effects of medications, and are also involved in a wide range of vital biological processes. The structure of this representative protein was solved by a team at the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California at Berkeley (UCB).


http://www.lbl.gov/Science-Articles/Archive/abc-cystic-fibrosis.html.


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